What are proanthocyanidins?

Proanthocyanidins (pronounced ‘pro-ann-tho-sai-an-i-dins’) are a diverse class of phytochemicals present in the fruits, bark, leaves, and seeds of many plants.  These powerful antioxidants provide protection against free radicals by reducing the amount of oxidative stress.

You have heard of Vitamin C and Vitamin but have you heard of proanthocyanidins?  Some studies by scientists have suggested that the the antioxidant power of proanthocyanidins is 20 times higher than Vitamin C and more than 50 times higher than vitamin E.

In addition to protecting from damaging free radicals, proanthocyanidins provide flavor and astringency to beverages such as wine, fruit juices and herbal teas.

Proanthocyanidins are very similar with only slight differences in the structure of each molecule.

What are proanthocyanidins

What are proanthocyanidins?   Proanthocyanidins range from individual units to many linked units (i.e. oligomers).  For example, when two flavonoids such as a catechin and epicatechin join together they form a proanthocyanidin.

A group from the USDA (United States Department of Agriculture) determined the amount of proanthocyanidins in common foods and published their work in the Journal of Nutrition.

The amount of proanthocyanidins in a fruit or vegetable can vary depending on how the plant was grown, harvested, and prepared.  However, the table below can serve as a guide to foods that are high in proanthocyanidins.

Here is a list of foods containing and beverages containing proanthocyanidins in order from most to least.

Proanthocyanidin content in common foods   [mg/100 g (fresh weight foods) mg/L (beverages)]
Food Total PAs
Cinnamon, ground 8108.2
Sorghum, sumac bran 3965.4
Grape seed (dry) 3532.3
Sorghum, sumac whole grain 1919.5
Baking chocolate, unsweetened 1635.9
Pinto beans, raw 796.3
Sorghum, hi-tannin whole grain 787.6
Choke berries 663.7
Red kidney beans 563.8
Grape juice 524
Hazelnuts 500.7
Pecans 494.1
Small red beans 456.6
Sorghum, hi-tannin whole grain extrudate 447.3
Cranberries 418.8
Blueberries, lowbush 331.9
Red wine 313
Plums, black diamond 256.6
Black chocolate 246
Black plums 237.9
Pistachios 237.3
Cranberry juice cocktail 231
Plums 215.9
Milk chocolate 192
Almonds 184
Blueberries, cultivated highbush 179.8
Blackcurrants 147.8
Strawberries 145
Apple, granny smith 141
Apple, red delicious, with peel 125.8
Apple, red delicious without peel 98.7
Apple, gala 92.4
Apple, golden delicious, with peel 91.1
Green grapes 81.5
Apple, golden delicious, without peel 80.4
Barley 74.2
Curry powder 74.2
Apple, fuji 69.6
Peaches 67.3
Walnuts 67.3
Red grapes 61
Apple sauce 47.2
Pears, green cultivars 42.3
Black eye peas 33.3
Pears 31.9
Raspberries 30.2
Blackberries 27
Pinto beans, simmered 2 h 26.3
Chocolate milk 26
Beer 23
Nectarines 22.8
Indian squash, raw 16.4
Apricots 15.6
Peanuts, roasted 15.6
Kiwis, gold 13.9
Peanut butter 13.2
Mangos 12.8
Dates, Deglet Noor (fresh) 10.7
Apple juice 9
Marion berries 8.9
Cashews 8.7
Cherries 8.2
Black beans 8.1
Avocados 7.4
Bananas 4
Kiwis 3.7
Peach, canned heavy syrup 2.9

Journal of Nutrition. 2004 March;Volume134 (Issue 3):  Pages 613-7.

Jeremy Johnson, PharmD, PhD


Categories: Plant Medicine