Butterbur for Migraines?

Butterbur (Petasites hybridus) is a perennial plant that grows in Europe, Asia and parts of North America.  Butterbur prefers growing in wet soil including marshes, damp forests, and along rivers.

Butterbur has been used as an herbal treatment for migraines, headaches, asthma, urinary tract infections, wounds, allergies, and upset stomach.

Herbal remedies may use the root, stem or leaf of the butterbur plant.

 

butterbur migraines

How does butterbur work for migraines?

Many phytochemicals are found in butterbur, however, two phytochemicals have gained interest for reducing migraine headaches.

The phytochemicals believed to help reduce the symptoms of migraines are petasin and isopetasin.

The exact mechanism is not understood, however, one idea is that butterbur can reduce inflammation.  This action is believed to be responsible for reducing headache frequency.

 

Are there side effects with Butterbur?

There is not much available for long-term use however some known side effects that are rare include:

Burping

Headaches

Difficulty breathing

Fatigue

Drowsiness

 

 

Who should not take butterbur?

Yes.  Our goal is always to error on the side of caution.

Women who are pregnant or nursing should not take butterbur.

Some ingredients in butterbur are similar to other plants that include borage, gravel root and ragwort. You should use only one at a time to avoid any side effects from taking too many petasins.

If you have liver disease you should speak with your doctor or pharmacist before taking butterbur.

 

Are there any safety concerns with butterbur?

Yes. You want to make sure that the product does not contain pyrrolizidine alkaloids (PAs).  Products are available on the market indicated to be free of pyrrolizidine alkaloids

The studies used in clinical trials were done with products that had the pyrrolizidine alkaloids removed.

Jeremy Johnson, PharmD, PhD


Categories: Ask the Pharmacist, Headaches, Migraines, Pain